Article
Baseline predictors of rates of hippocampal atrophy in mild cognitive impairment.
Neurology - 9 Oct 2007
van de Pol L A, van der Flier W M, Korf E S C, Fox N C, Barkhof F, Scheltens P
Abstract excerpt
OBJECTIVE: A large cohort of subjects with mild cognitive impairment (MCI) was categorized into tertiles based on hippocampal atrophy rates, as a proxy for Alzheimer-type pathology. We compared baseline clinical, neuropsychological, and MRI measures to characterize these MCI subgroups. METHODS: Serial MRI data of 323 subjects with MCI (49% men; mean +/- SD age: 69 +/- 9 years), followed for 2 years in a clinical...
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