Article
MRI of hippocampal volume loss in early Alzheimer's disease in relation to ApoE genotype and biomarkers.
Brain : a journal of neurology - 1 Apr 2009
Schuff N, Woerner N, Boreta L, Kornfield T, Shaw L M, Trojanowski J Q, Thompson P M, Jack C R, Weiner M W
Abstract excerpt
Hippocampal volume change over time, measured with MRI, has huge potential as a marker for Alzheimer's disease. The objectives of this study were: (i) to test if constant and accelerated hippocampal loss can be detected in Alzheimer's disease, mild cognitive impairment and normal ageing over short periods, e.g. 6-12 months, with MRI in the large multicentre setting of the Alzheimer's Disease Neuroimaging...
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