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Article

Whole-brain atrophy rate in Alzheimer disease: identifying fast progressors.

Neurology - 6 May 2008

Sluimer J D, Vrenken H, Blankenstein M A, Fox N C, Scheltens P, Barkhof F, van der Flier W M

Abstract excerpt

OBJECTIVE: To assess which baseline clinical and MRI measures influence whole-brain atrophy rates, measured from serial MR imaging. METHODS: We recruited 65 patients with Alzheimer disease (mean +/- SD age 70 +/- 8 y, 58% women, Mini-Mental State Examination [MMSE] 22 +/- 5), scanned with an average interval of 1.7 +/- 0.6 years. Whole-brain atrophy rates were used as outcome measure. Baseline normalized brain...

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Source

Identifiers

PMID: 18458218
DOI: 10.1212/01.wnl.0000311446.61861.e3

Genes

APOE

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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