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Article

Patterns of progressive atrophy vary with age in Alzheimer's disease patients.

Neurobiology of aging - 1 Mar 2018

Fiford Cassidy M, Ridgway Gerard R, Cash David M, Modat Marc, Nicholas Jennifer, Manning Emily N, Malone Ian B, Biessels Geert Jan, Ourselin Sebastien, Carmichael Owen T, Cardoso M Jorge, Barnes Josephine

Abstract excerpt

Age is not only the greatest risk factor for Alzheimer's disease (AD) but also a key modifier of disease presentation and progression. Here, we investigate how longitudinal atrophy patterns vary with age in mild cognitive impairment (MCI) and AD. Data comprised serial longitudinal 1.5-T magnetic resonance imaging scans from 153 AD, 339 MCI, and 191 control subjects. Voxel-wise maps of longitudinal volume change...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 29220823
DOI: 10.1016/j.neurobiolaging.2017.11.002
PMCID: PMC5805840

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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