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Article

Tracking atrophy progression in familial Alzheimer's disease: a serial MRI study.

The Lancet. Neurology - 1 Oct 2006

Ridha Basil H, Barnes Josephine, Bartlett Jonathan W, Godbolt Alison, Pepple Tracey, Rossor Martin N, Fox Nick C

Abstract excerpt

BACKGROUND: Serial MRI scanning of autosomal dominant mutation carriers for Alzheimer's disease provides an opportunity to track changes that could predate symptoms or clinical diagnosis of the disease. We used hierarchical modelling to assess how hippocampal and whole-brain volumes change as familial Alzheimer's disease progresses from the presymptomatic stage through to diagnosis. METHODS: Nine mutation...

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Identifiers

PMID: 16987729
DOI: 10.1016/S1474-4422(06)70550-6

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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