Article
Allelic loss and microsatellite instability in prostate cancers in Japan.
Oncology - 1 Jan 2000
Watanabe M, Shiraishi T, Muneyuki T, Nagai M, Fukutome K, Murata M, Kawamura J, Yatani R
Abstract excerpt
A series of 25 primary prostate cancers in Japanese were screened for loss of heterozygosity and microsatellite instability using twelve microsatellite markers containing APC, DCC, TP53, BRCA1, and BRCA2. Frequent loss of heterozygosity was observed for D8S201 (48%), LPL (48%), and DCC (26%). In...
Topics
- Adult
- Aged
- Aged, 80 and over
- Alleles
- Chromosomes, Human, Pair 17
- Chromosomes, Human, Pair 8
- DNA, Neoplasm
- Genes, Tumor Suppressor
- Genetic Markers
- Humans
- Loss of Heterozygosity
- Male
- Microsatellite Repeats
- Middle Aged
- Polymerase Chain Reaction
- Prostatic Neoplasms