Article
Allelic imbalance in the clonal evolution of prostate carcinoma.
Cancer - 1 May 1999
Cheng L, Bostwick D G, Li G, Wang Q, Hu N, Vortmeyer A O, Zhuang Z
Abstract excerpt
BACKGROUND: To understand better the genetic basis of the clonal evolution of prostate carcinoma, the authors analyzed the pattern of allelic loss in 25 matched primary and metastatic prostate tumors. METHODS: Twenty-five cases were selected from the surgical pathology files of the Mayo Clinic from patients who had undergone radical retropubic prostatectomy and bilateral lymphadenectomy between 1987-1991. All...
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