Article
Allelic loss on chromosomes 8p, 22q and 18q (DCC) in human prostate cancer.
International journal of cancer - 22 Aug 1996
Crundwell M C, Chughtai S, Knowles M, Takle L, Luscombe M, Neoptolemos J P, Morton D G, Phillips S M
Abstract excerpt
Previous studies have suggested the involvement of tumour-suppressor genes on chromosomes 8p, 22q and 18q (DCC) in prostate cancer. The aim of this study was to further characterize these regions. We investigated 20 polymorphic regions on the 3 chromosome arms in 43 cancers and 10 cases of benign...
Topics
- Aged
- Aged, 80 and over
- Alleles
- Base Sequence
- Chromosomes, Human, Pair 18
- Chromosomes, Human, Pair 22
- Chromosomes, Human, Pair 8
- Gene Deletion
- Humans
- Male
- Microsatellite Repeats
- Middle Aged
- Molecular Sequence Data
- Prostatic Hyperplasia
- Prostatic Neoplasms