Microsatellite instability and other molecular abnormalities in human prostate cancer.

doi:10.1111/j.1349-7006.1995.tb03007.x

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Article

Microsatellite instability and other molecular abnormalities in human prostate cancer.

Japanese journal of cancer research : Gann - 1 Oct 1995

Suzuki H, Komiya A, Aida S, Akimoto S, Shiraishi T, Yatani R, Igarashi T, Shimazaki J

Abstract excerpt

Microsatellites are highly polymorphic, short-tandem repeat sequences dispersed throughout the genome. Instability of these repeat sequences at multiple genetic loci may result from mismatch repair errors, and occurs in hereditary nonpolyposis colorectal carcinoma and certain sporadic cancers. To...

Topics

Adenocarcinoma
DNA, Neoplasm
Genes, p53
Genetic Markers
Humans
Japan
Male
Microsatellite Repeats
Mutation
Polymorphism, Single-Stranded Conformational
Prostatic Neoplasms
Receptors, Androgen

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