Article
Microsatellite instability in human prostate cancer.
British journal of cancer - 1 Sept 1995
Watanabe M, Imai H, Shiraishi T, Shimazaki J, Kotake T, Yatani R
Abstract excerpt
Microsatellite instability (MSI) was examined at 36 loci, and found in 9 (43%) of the 21 prostatic cancers. A loss of heterozygosity had occurred in five cases (24%). MSI did not correlate with clinical stage, but might play a role in the development of a subset of prostate cancers.
Topics
- Adult
- Aged
- Aged, 80 and over
- Alleles
- DNA, Neoplasm
- DNA, Satellite
- Drug Stability
- Gene Deletion
- Heterozygote
- Humans
- Male
- Middle Aged
- Prostatic Neoplasms