Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

PRLTS gene alterations in human prostate cancer.

Japanese journal of cancer research : Gann - 1 Apr 1997

Komiya A, Suzuki H, Ueda T, Aida S, Ito N, Shiraishi T, Yatani R, Emi M, Yasuda K, Shimazaki J, Ito H

Abstract excerpt

Since loss of heterozygosity on 8p22-p21.3 has been found frequently in prostate cancer, the status of a candidate tumor suppressor gene named PRLTS gene, recently cloned from the same region in some human malignancies, was examined in the present study. DNAs were isolated from 69 Japanese prostate cancer patients (37 localized and 32 cancer-death cases). Loss of heterozygosity at this gene locus was observed in...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Adenocarcinoma
Share to Alleles
Share to Cell Differentiation

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to DNA Mutational Analysis

Share to Gene Deletion

Share to Genes, Tumor Suppressor

Share to Polymorphism, Single-Stranded Conformational

Share to Prostatic Neoplasms

Source

Open in PubMed Open full text

Identifiers

PMID: 9197531
DOI: 10.1111/j.1349-7006.1997.tb00394.x
PMCID: PMC5921422

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

PRLTS gene alterations in human prostate cancer.PMID 9197531Read ↗

Allelic loss and microsatellite instability in prostate cancers in Japan.Semantic proximity Read ↗

Germline sequence variants of the LZTS1 gene are associated with prostate cancer risk.Semantic proximity Read ↗

Isolation of a candidate tumor suppressor gene on chromosome 8p21.3-p22 that is homologous to an extracellular domain of the PDGF receptor beta gene.Semantic proximity Read ↗

Identification of the gene for a novel liver-related putative tumor suppressor at a high-frequency loss of heterozygosity region of chromosome 8p23 in human hepatocellular carcinomaSemantic proximity Read ↗

Homozygous deletions at 8p22 and 8p21 in prostate cancer implicate these regions as the sites for candidate tumor suppressor genes.Semantic proximity Read ↗

Homozygous deletion and frequent allelic loss of chromosome 8p22 loci in human prostate cancer.Semantic proximity Read ↗

Analysis of 99 microdissected prostate carcinomas reveals a high frequency of allelic loss on chromosome 8p12-21.Semantic proximity Read ↗

Allelotyping analysis at chromosome arm 8p of high-grade prostatic intraepithelial neoplasia and incidental, latent, and clinical prostate cancers.Semantic proximity Read ↗

Loss of heterozygosity of the BRCA1 and other loci on chromosome 17q in human prostate cancer.Semantic proximity Read ↗

TMPRSS2 Met160Val polymorphism: significant association with sporadic prostate cancer, but not with latent prostate cancer in Japanese men.Semantic proximity Read ↗

Loss of heterozygosity at the thymidylate synthase (TS) locus on chromosome 18 affects tumor response and survival in individuals heterozygous for a 28-bp polymorphism in the TS gene.Semantic proximity Read ↗

Mutation and expression analysis of LZTS1 in ovarian cancer.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.