Frequent loss of expression and loss of heterozygosity of the putative tumor suppressor gene DCC in prostatic carcinomas.

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Article

Frequent loss of expression and loss of heterozygosity of the putative tumor suppressor gene DCC in prostatic carcinomas.

Cancer research - 15 Jun 1993

Gao X, Honn K V, Grignon D, Sakr W, Chen Y Q

Abstract excerpt

The putative tumor suppressor gene DCC has been shown to be frequently lost or expressed at low levels in colorectal, gastric, pancreatic, and esophageal carcinomas. In the present study, the DCC gene and its mRNA expression in human and rat prostatic carcinoma cells as well as in prostatic carci...

Topics

Alleles
Animals
Base Sequence
Down-Regulation
Gene Deletion
Gene Expression Regulation, Neoplastic
Genes, Tumor Suppressor
Humans
Male
Molecular Sequence Data
Polymerase Chain Reaction
Prostatic Neoplasms
RNA, Messenger
RNA, Neoplasm
Rats
Transcription, Genetic
Tumor Cells, Cultured

Source

Open in PubMed

Identifiers

PMID: 8504411

Genes

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-8504411-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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