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Article

The Polycomb-group gene eed is required for normal morphogenetic movements during gastrulation in the mouse embryo.

Development (Cambridge, England) - 1 Nov 1998

Faust C, Lawson K A, Schork N J, Thiel B, Magnuson T

Abstract excerpt

We have characterized an induced mutation, called embryonic ectoderm development or eed, that disrupts A-P patterning of the mouse embryo during gastrulation. Positional cloning of this gene revealed it to be the highly conserved homologue of the Drosophila gene extra sex combs, which is required for maintenance of long-term transcriptional repression of homeotic gene expression. Mouse embryos homozygous for...

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Identifiers

PMID: 9778508
DOI: 10.1242/dev.125.22.4495

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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