Article
CYP2D6 and CYP2C19 genotypes in an elderly Swedish population.
European journal of clinical pharmacology - 1 Aug 1998
Yamada H, Dahl M L, Lannfelt L, Viitanen M, Winblad B, Sjöqvist F
Abstract excerpt
OBJECTIVE: Eighty-three healthy elderly Swedish subjects (age 87 +/- 4 years, mean +/- SD, range 80-98 years) were genotyped with respect to the two genetic polymorphisms of oxidative drug metabolism, CYP2D6 and CYP2C19, using allele-specific polymerase chain reaction (PCR). A control population consisted of 248 younger unrelated healthy volunteers (age 31 +/- 9 years, range 19-63 years) for CYP2D6, and 162 (age...
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