Article
CYP2D6 and CYP2C19 genotypes in an elderly Swedish population.
European journal of clinical pharmacology - 1 Aug 1998
Yamada H, Dahl M L, Lannfelt L, Viitanen M, Winblad B, Sjöqvist F
Abstract excerpt
OBJECTIVE: Eighty-three healthy elderly Swedish subjects (age 87 +/- 4 years, mean +/- SD, range 80-98 years) were genotyped with respect to the two genetic polymorphisms of oxidative drug metabolism, CYP2D6 and CYP2C19, using allele-specific polymerase chain reaction (PCR). A control population...
Topics
- Adult
- Age Factors
- Aged
- Aged, 80 and over
- Aryl Hydrocarbon Hydroxylases
- Case-Control Studies
- Cytochrome P-450 CYP2C19
- Cytochrome P-450 CYP2D6
- Cytochrome P-450 Enzyme System
- Dementia
- Female
- Genotype
- Humans
- Male
- Middle Aged
- Mixed Function Oxygenases
- Polymerase Chain Reaction
- Reference Values
