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Article

Cytochrome P450 CYP2C19 genotypes in Nigerian sickle-cell disease patients and normal controls.

Journal of clinical pharmacy and therapeutics - 1 Aug 2010

Babalola C P, Adejumo O, Ung D, Xu Z, Odetunde A, Kotila T, Falusi A G, Nagar S

Abstract excerpt

BACKGROUND AND OBJECTIVE: Subjects with different CYP2C19 genotypes may metabolize proguanil, a pro-drug used for malaria prophylaxis differently and the frequency of the different alleles may be different in patients with sickle-cell disease (SCD) and normal controls. The objective of this study was to evaluate CYP2C19 *1, *2 and *3 allele and genotype frequencies in Nigerian normal controls and SCD patients,...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 20831548
DOI: 10.1111/j.1365-2710.2009.01122.x

Genes

SCD

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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