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Article

Allele and genotype frequencies of CYP2C9, CYP2C19 and CYP2D6 in an Italian population.

Pharmacological research - 1 Aug 2004

Scordo Maria Gabriella, Caputi Achille P, D'Arrigo Concetta, Fava Giuseppina, Spina Edoardo

Abstract excerpt

The polymorphic cytochrome P450 isoenzymes (CYPs) 2C9, 2C19 and 2D6 metabolise many important drugs, as well as other xenobiotics. Their polymorphism gives rise to important interindividual and interethnic variability in the metabolism and disposition of several therapeutic agents and may cause differences in the clinical response to these drugs. In this study, we determined the genotype profile of a random...

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Identifiers

PMID: 15177309
DOI: 10.1016/j.phrs.2004.01.004

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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