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Article

Low frequency of defective alleles of cytochrome P450 enzymes 2C19 and 2D6 in the Turkish population.

Clinical pharmacology and therapeutics - 1 Aug 1999

Aynacioglu A S, Sachse C, Bozkurt A, Kortunay S, Nacak M, Schröder T, Kayaalp S O, Roots I, Brockmöller J

Abstract excerpt

BACKGROUND AND OBJECTIVES: The genetically polymorphic cytochrome P450 enzymes 2Cl9 (CYP2Cl9) and 2D6 (CYP2D6) contribute to the metabolism of about 30% of all drugs. For analysis of the ethnic-related differences in drug disposition and as a preparation for routine genotyping, we examined CYP2C19 and CYP2D6 mutations in a large Turkish population. METHODS: CYP2C19 and CYP2D6 alleles were determined with use of...

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Identifiers

PMID: 10460072
DOI: 10.1053/cp.1999.v66.100072001

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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