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Article

Falls: The Adverse Drug Reaction of the Elderly and the Impact of Pharmacogenetics

1 Aug 2017

Abstract excerpt

Falls is a frequent type of adverse drug reactions causing significant morbidity and mortality in the elderly. We reviewed, with which drugs the risk of falls is relevant and might depend on genomic variation. Pharmacogenetic variability may contribute to drug-induced falls for instance mediated by impaired drug elimination due to inherited deficiency in enzymes like CYP2C9, CYP2C19 and CYP2D6. The relative role...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 28776468
DOI: 10.2217/pgs-2017-0018

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