Article
CYP2D6, NAT2 and CYP2E1 genetic polymorphisms in nonagenarians.
Age and ageing - 1 Mar 1997
Agúndez J A, Rodríguez I, Olivera M, Ladero J M, García M A, Ribera J M, Benítez J
Abstract excerpt
BACKGROUND: enzymatic polymorphisms affecting the metabolic disposition of xenobiotics may modulate the rate of activation or deactivation of carcinogens and other toxic environmental chemicals. Hence, these polymorphisms may influence the risk of suffering some types of cancer and other degenerative diseases that are incompatible with extreme longevity. AIMS: to establish the distribution of three well known...
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