Genotypes for the cytochrome P450 enzymes CYP2D6 and CYP2C19 in human longevitY. Role of CYP2D6 and CYP2C19 in longevity.

doi:10.1007/s002280050487

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Article

Genotypes for the cytochrome P450 enzymes CYP2D6 and CYP2C19 in human longevitY. Role of CYP2D6 and CYP2C19 in longevity.

European journal of clinical pharmacology - 1 Jul 1998

Bathum L, Andersen-Ranberg K, Boldsen J, Brøsen K, Jeune B

Abstract excerpt

OBJECTIVE: To test whether some genotypes for CYP2D6 or CYP2C19 could contribute to longevity, we genotyped 241 Danish nonagenarians and centenarians for CYP2D6 and CYP2C19. METHODS: For CYP2D6 we identified the alleles CYP2D6*1, CYP2D6*3 and CYP2D6*4 with allele-specific polymerase chain reactio...

Topics

Adult
Aged
Aged, 80 and over
Aging
Alleles
Aryl Hydrocarbon Hydroxylases
Cytochrome P-450 CYP2C19
Cytochrome P-450 CYP2D6
Cytochrome P-450 Enzyme System
DNA
Female
Genotype
Humans
Longevity
Male
Middle Aged
Mixed Function Oxygenases

Source

Open in PubMed

Identifiers

PMID: 9754988
DOI: 10.1007/s002280050487

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-9754988-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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