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Article

Cytochrome p450 polymorphisms in geriatric patients: impact on adverse drug reactions--a pilot study.

Drugs & aging - 1 Jan 2005

Egger Tobias, Dormann Harald, Ahne Gabi, Pahl Andreas, Runge Ulrich, Azaz-Livshits Tanya, Neubert Antje, Criegee-Rieck Manfred, Gassmann Karl G, Brune Kay

Abstract excerpt

BACKGROUND AND OBJECTIVE: Up to 23% of the population, depending on their ethnic background, has genetically determined differences in the metabolism of drugs by the cytochrome P450 (CYP) enzymes CYP2C9, CYP2C19 and CYP2D6. The aim of this survey was to determine the relationship between genetical polymorphisms in these CYP enzymes and adverse drug reactions (ADRs) in geriatric patients. STUDY DESIGN: In a...

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Identifiers

PMID: 15813658
DOI: 10.2165/00002512-200522030-00007

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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