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Article

Exploring functional redundancy in the immunoglobulin mu heavy-chain gene enhancer.

Molecular and cellular biology - 1 Nov 1998

Dang W, Nikolajczyk B S, Sen R

Abstract excerpt

Immunoglobulin (Ig) mu heavy-chain gene enhancer activity is mediated by multiple DNA binding proteins. Mutations of several protein binding sites in the enhancer do not affect enhancer activity significantly. This feature, termed redundancy, is thought to be due to functional compensation of the mutated sites by other elements within the enhancer. In this study, we identified the elements that make the basic...

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Identifiers

PMID: 9774700
DOI: 10.1128/MCB.18.11.6870
PMCID: PMC109270

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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