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Article

Selective utilization of basic helix-loop-helix-leucine zipper proteins at the immunoglobulin heavy-chain enhancer.

Molecular and cellular biology - 1 Jan 1997

Carter R S, Ordentlich P, Kadesch T

Abstract excerpt

The microE3 E box within the immunoglobulin heavy-chain (IgH) enhancer binds several proteins of the basic helix-loop-helix-leucine zipper (bHLHzip) class, including TFE3, USF1, and Max. Both TFE3 and USF have been described as transcriptional activators, and so we investigated their possible roles in activating the IgH enhancer in vivo. Although TFE3 activated various enhancer-based reporters, both USF1 and Max...

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Identifiers

PMID: 8972181
DOI: 10.1128/MCB.17.1.18
PMCID: PMC231725

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