Article
Two conserved essential motifs of the murine immunoglobulin lambda enhancers bind B-cell-specific factors.
Molecular and cellular biology - 1 Jan 1992
Rudin C M, Storb U
Abstract excerpt
Two highly homologous enhancers associated with the two murine immunoglobulin lambda constant-region clusters were recently identified. In order to better understand the molecular basis for the developmental stage- and cell-type-restricted expression of lambda genes, we have undertaken an analysi...
Topics
- Animals
- B-Lymphocytes
- Base Sequence
- Binding Sites
- DNA
- Deoxyribonuclease I
- Enhancer Elements, Genetic
- Gene Expression Regulation
- Immunoglobulin Light Chains
- Immunoglobulin lambda-Chains
- Macromolecular Substances
- Mice
- Molecular Sequence Data
- Mutation
- Transcription Factors
- Transfection
- Tumor Cells, Cultured