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Article

Two conserved essential motifs of the murine immunoglobulin lambda enhancers bind B-cell-specific factors.

Molecular and cellular biology - 1 Jan 1992

Rudin C M, Storb U

Abstract excerpt

Two highly homologous enhancers associated with the two murine immunoglobulin lambda constant-region clusters were recently identified. In order to better understand the molecular basis for the developmental stage- and cell-type-restricted expression of lambda genes, we have undertaken an analysis of the putative regulatory domains of these enhancers. By using a combination of DNase I footprinting,...

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Identifiers

PMID: 1729607
DOI: 10.1128/mcb.12.1.309-320.1992
PMCID: PMC364111

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