Article
Pi, a pre-B-cell-specific enhancer element in the immunoglobulin heavy-chain enhancer.
Molecular and cellular biology - 1 Oct 1993
Libermann T A, Baltimore D
Abstract excerpt
We have identified a new immunoglobulin heavy-chain enhancer element, designated pi, between the microE2 and microE3 elements. The pi enhancer element is transcriptionally active primarily during early stages of B-cell development but becomes virtually inactive during B-cell maturation at about the stage of immunoglobulin kappa light-chain gene rearrangement. Mutational analysis suggests that the pi element is...
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