Article
Context dependent transactivation domains activate the immunoglobulin mu heavy chain gene enhancer.
The EMBO journal - 2 Sept 1996
Erman B, Sen R
Abstract excerpt
Enhancers and promoters nucleate the assembly of multiprotein complexes that are required for the transcriptional activation of eukaryotic genes. Although multimerized binding sites of individual transcription factors sometimes mimic the properties of an enhancer, the combinatorial use of factors...
Topics
- Enhancer Elements, Genetic
- Immunoglobulin mu-Chains
- Mutation
- Proto-Oncogene Protein c-ets-1
- Proto-Oncogene Proteins
- Proto-Oncogene Proteins c-ets
- Sequence Deletion
- Transcription Factors
- Transcriptional Activation