Article
Phosphorylation regulates human T-cell leukemia virus type 1 Rex function.
Retrovirology - 17 Nov 2009
Kesic Matthew, Doueiri Rami, Ward Michael, Semmes O John, Green Patrick L
Abstract excerpt
BACKGROUND: Human T-cell leukemia virus type 1 (HTLV-1) is a pathogenic complex deltaretrovirus, which is the causative agent of adult T-cell leukemia/lymphoma (ATL) and HTLV-1-associated myelopathy/tropical spastic paraparesis. In addition to the structural and enzymatic viral gene products, HTLV-1 encodes the positive regulatory proteins Tax and Rex along with viral accessory proteins. Tax and Rex proteins...
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