Article
Dominant negative mutants of human T-cell leukemia virus type I Rex and human immunodeficiency virus type 1 Rev fail to multimerize in vivo.
Journal of virology - 1 May 1993
Bogerd H, Greene W C
Abstract excerpt
Human T-cell leukemia virus type I (HTLV-I) Rex and human immunodeficiency virus type 1 (HIV-1) Rev are essential gene products required for the replication of these two pathogenic human retroviruses. Both Rex and Rev act at a posttranscriptional level by binding to highly structured RNA-response...
Topics
- Acquired Immunodeficiency Syndrome
- Amino Acid Sequence
- Chloramphenicol O-Acetyltransferase
- DNA-Binding Proteins
- Fungal Proteins
- Gene Products, rev
- Gene Products, rex
- HIV-1
- Herpes Simplex Virus Protein Vmw65
- Human T-lymphotropic virus 1
- Macromolecular Substances
- Molecular Sequence Data
- Mutation
- Recombinant Fusion Proteins
- Saccharomyces cerevisiae Proteins
- Transcription Factors
- Transcriptional Activation
- Transfection