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Article

Chloroquine modulation of specific metabolizing enzymes activities: investigation with selective five drug cocktail.

British journal of clinical pharmacology - 1 Sept 1998

Adedoyin A, Frye R F, Mauro K, Branch R A

Abstract excerpt

AIMS: The aim of this study was to investigate whether chloroquine can inhibit drug metabolism in humans, if such inhibition is general or selective for certain enzymes and evaluate the potential for and clinical significance of any drug-drug interactions when chloroquine is co-administered with other drugs. METHODS: The study was conducted in fourteen normal non-smoking healthy male volunteers using a cocktail...

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Identifiers

PMID: 9764961
DOI: 10.1046/j.1365-2125.1998.00765.x
PMCID: PMC1873674

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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