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Article

Endogenous p53 regulation and function in early stage Friend virus-induced tumor progression differs from that following DNA damage.

Oncogene - 3 Sept 1998

Kelley L L, Hicks G G, Hsieh F F, Prasher J M, Green W F, Miller M D, Eide E J, Ruley H E

Abstract excerpt

Erythroleukemia induced by the anemia strain of Friend virus occurs in two stages. The first stage results in rapid expansion of pre-leukemic proerythroblasts (FVA cells) dependent on erythropoietin (Epo) for differentiation and survival in vitro. The second stage is characterized by emergence of erythroleukemic clones (MEL cells) which typically bear activation of the ets-oncogene, PU.1/spi.1, and loss of...

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Identifiers

PMID: 9764822
DOI: 10.1038/sj.onc.1202037

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Endogenous p53 regulation and function in early stage Friend virus-induced tumor progression differs from that following DNA damage.PMID 9764822Read ↗

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