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Article

Loss of p53 tumor suppressor function is required for in vivo progression of Friend erythroleukemia.

Oncogene - 24 May 2001

Prasher J M, Elenitoba-Johnson K S, Kelley L L

Abstract excerpt

A role for p53 in the in vivo progression of Friend virus-induced erythroleukemia has been suggested but not clearly defined. We developed a Friend virus-sensitive, p53-deficient mouse model to directly address the role of p53 in Friend erythroleukemia. When infected with the polycythemia-inducing strain of Friend virus (FVP), p53 null mice exhibited accelerated progression to erythroleukemia and accelerated...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 11420707
DOI: 10.1038/sj.onc.1204395

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Loss of p53 tumor suppressor function is required for in vivo progression of Friend erythroleukemia.PMID 11420707Read ↗

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