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Article

Friend virus induced murine erythroleukaemia: the p53 locus.

Cancer surveys - 1 Jan 1992

Johnson P, Benchimol S

Abstract excerpt

The development of Friend virus induced murine erythroleukaemia is associated with specific genetic events. One of these events is loss of wild type p53 expression, which can occur by internal deletion or proviral insertion in the p53 gene and by single point mutations in the coding sequence. In all cases, the corresponding wild type allele is absent. The high frequency of observed p53 mutations strongly suggests...

Topics

Alleles
Animals
Friend murine leukemia virus
Gene Expression Regulation, Neoplastic
Gene Expression Regulation, Viral
Genes, Dominant
Genes, p53
Leukemia, Experimental
Mice
Mutation
Spleen Focus-Forming Viruses

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 1638545

Genes

EPO

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-1638545-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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Friend virus induced murine erythroleukaemia: the p53 locus.PMID 1638545Read ↗

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