Article
Major histocompatibility complex class II alleles and the course and outcome of MS: a population-based study.
Neurology - 1 Sept 1998
Weinshenker B G, Santrach P, Bissonet A S, McDonnell S K, Schaid D, Moore S B, Rodriguez M
Abstract excerpt
BACKGROUND: The major histocompatibility complex (MHC) has been consistently associated with susceptibility to MS and the course of several other human autoimmune diseases. A putative association between the course and severity of MS and the MHC remains controversial. METHODS: DR and DQ genotyping by either restriction fragment length polymorphism or sequence-specific PCR-based typing in 119 patients representing...
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