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Article

Genetic variants of Complex I in multiple sclerosis.

Journal of the neurological sciences - 15 Jan 2005

Vyshkina Tamara, Banisor Ileana, Shugart Yin Yao, Leist Thomas P, Kalman Bernadette

Abstract excerpt

HYPOTHESIS: A mitochondrial mechanism contributes to neurodegeneration in multiple sclerosis (MS). Genetic variants of Complex I genes may influence the nature of tissue response to inflammation in the central nervous system (CNS). BACKGROUND: Complex I is encoded by seven mitochondrial and 38 nuclear genes. Many of the nuclear genes colocalize with regions where full genome scans detected linkage in MS. Previous...

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Share to Gene Frequency
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 15607211
DOI: 10.1016/j.jns.2004.09.027

Genes

NDUFA7
NDUFS5
NDUFS7

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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