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Article

Evidence for additional genetic risk indicators of relapse-onset MS within the HLA region.

Neurology - 27 Aug 2002

de Jong B A, Huizinga T W J, Zanelli E, Giphart M J, Bollen E L E M, Uitdehaag B M J, Polman C H, Westendorp R G J

Abstract excerpt

BACKGROUND: Human leukocyte antigen (HLA)-DR2 carriership is associated with an increased risk for MS. Genome searches using microsatellite markers have consistently shown that additional genetic factors contribute to susceptibility for MS. OBJECTIVE: To identify loci within the HLA region that predispose to relapse-onset MS independently of HLA-DR2. METHOD: A case-control study involving 159 patients with...

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Identifiers

PMID: 12196647
DOI: 10.1212/wnl.59.4.549

Genes

TNF

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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