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Article

Role of genetic susceptibility variants in predicting clinical course in multiple sclerosis: a cohort study.

Journal of neurology, neurosurgery, and psychiatry - 1 Nov 2016

Pan Gongbu, Simpson Steve, van der Mei Ingrid, Charlesworth Jac C, Lucas Robyn, Ponsonby Anne-Louise, Zhou Yuan, Wu Feitong, Taylor Bruce V

Abstract excerpt

BACKGROUND: The genetic drivers of multiple sclerosis (MS) clinical course are essentially unknown with limited data arising from severity and clinical phenotype analyses in genome-wide association studies. METHODS: Prospective cohort study of 127 first demyelinating events with genotype data, where 116 MS risk-associated single nucleotide polymorphisms (SNPs) were assessed as predictors of conversion to MS,...

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Identifiers

PMID: 27559181
DOI: 10.1136/jnnp-2016-313722

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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