Enhanced phenotypic expression of alpha-1-antitrypsin deficiency in an MZ heterozygote with chronic hepatitis C.

doi:10.1111/j.1572-0241.1998.00478.x

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Article

Enhanced phenotypic expression of alpha-1-antitrypsin deficiency in an MZ heterozygote with chronic hepatitis C.

The American journal of gastroenterology - 1 Sept 1998

Banner B F, Karamitsios N, Smith L, Bonkovsky H L

Abstract excerpt

A middle-aged white man of Scotch-Irish ancestry, being treated for chronic hepatitis C, was found to be heterozygous for alpha1-antitrypsin deficiency (PiMZ phenotype) after diagnostic PAS-positive, diastase-resistant globules were detected in a liver biopsy. The globules had not been present in...

Topics

Adult
Alanine Transaminase
Antiviral Agents
Aspartate Aminotransferases
Biopsy
Hepatitis C, Chronic
Heterozygote
Humans
Interferon-alpha
Liver
Male
Phenotype
alpha 1-Antitrypsin Deficiency

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