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Article

Increased PiZ gene frequency for alpha 1 antitrypsin in patients with genetic haemochromatosis.

Gut - 1 Jun 1995

Elzouki A N, Hultcrantz R, Stål P, Befrits R, Eriksson S

Abstract excerpt

The putative relationship between genetic haemochromatosis and PiZ alpha 1 antitrypsin deficiency was studied using a monoclonal antibody against the PiZ variant in 67 consecutive patients with genetic haemochromatosis seen at Karolinska Hospital and Huddinge University Hospital, Stockholm over a 10 year period. Three (4.5%) of the patients with haemochromatosis were found to be PiZ homozygotes (odds ratio = 82,...

Topics

Adult
Aged
Carcinoma, Hepatocellular
Female
Gene Frequency
Hemochromatosis
Heterozygote
Homozygote
Humans
Liver Cirrhosis
Liver Neoplasms
Male

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Middle Aged

Phenotype

alpha 1-Antitrypsin Deficiency

Source

Open in PubMed Open full text

Identifiers

PMID: 7615285
DOI: 10.1136/gut.36.6.922
PMCID: PMC1382634

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-7615285-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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