Article
[Liver changes in heterozygote alpha 1-antitrypsin deficiency PiZ].
Der Pathologe - 1 Nov 2000
Zhou H, Fischer H P
Abstract excerpt
Whether heterozygotes with alpha-1-antitrypsin (AAT) deficiency type PiZ bear an increased risk for chronic liver disease is controversial. On the basis of liver tissue from 1,030 autopsies (autopsy series), 1,847 biopsies (biopsy series) and 317 primary liver carcinomas (tumor series), we analysed the effect of heterozygous state PiZ for the development of liver diseases. The PiZ status was screened...
Topics
- Adult
- Aged
- Aged, 80 and over
- Autopsy
- Biopsy
- Hepatocytes
- Heterozygote
- Homozygote
- Humans
- Liver
- Liver Diseases
- Liver Neoplasms
- Middle Aged
- Phenotype
- Reference Values
- Retrospective Studies
- alpha 1-Antitrypsin Deficiency
