Article
Does alpha1-antitrypsin phenotype PiMZ increase the risk of fibrosis in liver disease due to hepatitis C virus infection?
European journal of gastroenterology & hepatology - 1 May 2006
Scott Brian B, Egner William
Abstract excerpt
BACKGROUND: The factors influencing the development of hepatic fibrosis, a key factor in determining outcome, are incompletely understood in hepatitis C. It has been suggested that the heterozygous Z mutation of the alpha1-antitrypsin gene (PiMZ) predisposes to more severe liver damage when infected by the hepatitis C virus. This retrospective cross-sectional study was designed to compare the prevalence of PiMZ...
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