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Article

Does the heterozygous state of alpha-1 antitrypsin deficiency have a role in chronic liver diseases? Interim results of a large case-control study.

Journal of pediatric gastroenterology and nutrition - 1 Jul 2006

Regev Arie, Guaqueta Constanza, Molina Enrique G, Conrad Andrew, Mishra Vishnu, Brantly Mark L, Torres Maria, De Medina Maria, Tzakis Andreas G, Schiff Eugene R

Abstract excerpt

BACKGROUND: The role of the heterozygous PiZ state of alpha-1 antitrypsin deficiency (alpha1ATD) in the pathogenesis of chronic liver disease (LD) is still a matter of controversy. AIM: To determine the prevalence of alpha1ATD heterozygote states in a large population of patients with established LD compared with individuals with no LD, and to determine whether the prevalence of PiZ is increased in patients with...

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Identifiers

PMID: 16819398
DOI: 10.1097/01.mpg.0000226387.56612.1e

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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