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Article

Chronic liver disease in heterozygous alpha1-antitrypsin deficiency PiZ.

Journal of hepatology - 1 Dec 2000

Fischer H P, Ortiz-Pallardó M E, Ko Y, Esch C, Zhou H

Abstract excerpt

BACKGROUND/AIMS: The contribution of the heterozygous state PiZ of alpha1-antitrypsin deficiency (AATD) to the pathogenesis of chronic liver disease is debated. We analyzed whether patients with this genetic defect carrying a single PiZ gene are at increased risk for developing chronic liver disease. METHODS: 1847 consecutive biopsy cases and 1030 autopsy cases of Caucasian adults were screened...

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Identifiers

PMID: 11131449
DOI: 10.1016/s0168-8278(00)80119-1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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