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Article

Multiple endocrine neoplasia type 1 (MEN1): LOH studies in a affected family and in sporadic cases.

Anticancer research - 1 Jan 2000

Valdes N, Alvarez V, Diaz-Cadorniga F, Aller J, Villazon F, Garcia I, Herrero A, Coto E

Abstract excerpt

Multiple endocrine neoplasia (Menl) is an autosomai dominant hereditary trait characterized by tumors of endocrine tissues. The MEN1 gene maps to chromosome llql3, has been recently isolated, and encodes a protein termed menin that is ubiquitously expressed. This gene is likely to be a tumor suppressor gene, with tumors developing after the inactivation of both copies of the gene in a single cell. In agreement...

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Identifiers

PMID: 9703929

Genes

MEN1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Multiple endocrine neoplasia type 1 (MEN1): LOH studies in a affected family and in sporadic cases.PMID 9703929Read ↗

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Loss of heterozygosity in sporadic parathyroid tumours: involvement of chromosome 1 and the MEN1 gene locus in 11q13.Semantic proximity Read ↗

MEN1 mutation analysis in Chinese patients with multiple endocrine neoplasia type 1.Semantic proximity Read ↗

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Review: multiple endocrine neoplasia type 1, sporadic neuroendocrine tumors, and MENIN.Semantic proximity Read ↗

MEN1 gene and its mutations: basic and clinical implications.Semantic proximity Read ↗

Six novel MEN1 gene mutations in sporadic parathyroid tumors.Semantic proximity Read ↗

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