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Article

MEN1 gene alterations do not correlate with the phenotype of sporadic primary hyperparathyroidism.

Journal of endocrinological investigation - 1 Jun 2002

Cetani F, Pardi E, Vignali E, Borsari S, Picone A, Cianferotti L, Ambrogini E, Miccoli P, Pinchera A, Marcocci C

Abstract excerpt

Loss of heterozygosity (LOH) in the MEN1 region on chromosome 11q13 and MEN1 gene mutations have been found in a subset of sporadic parathyroid tumors. The question of whether these genetic abnormalities in the parathyroid tumors might influence the clinical and biochemical characteristics of primary hyperparathyroidism (PHPT) remains to be elucidated. The aim of the present study was to correlate the presence of...

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Source

Identifiers

PMID: 12109621
DOI: 10.1007/BF03345492

Genes

MEN1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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MEN1 gene alterations do not correlate with the phenotype of sporadic primary hyperparathyroidism.PMID 12109621Read ↗

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Novel somatic MEN1 gene alterations in sporadic primary hyperparathyroidism and correlation with clinical characteristics.Semantic proximity Read ↗

The MEN1 gene and associated diseases: an update.Semantic proximity Read ↗

Somatic mutation of the MEN1 gene in parathyroid tumours.Semantic proximity Read ↗

Screening of the Men1 gene and discovery of germ-line and somatic mutations in apparently sporadic parathyroid tumors.Semantic proximity Read ↗

Loss of heterozygosity in sporadic parathyroid tumours: involvement of chromosome 1 and the MEN1 gene locus in 11q13.Semantic proximity Read ↗

Analysis of genotype-phenotype correlations and survival outcomes in patients with primary hyperparathyroidism caused by multiple endocrine neoplasia type 1: the experience at a single institution.Semantic proximity Read ↗

Deletion of chromosome 1, but not mutation of MEN-1, predicts prognosis in sporadic pancreatic endocrine tumors.Semantic proximity Read ↗

Localization of the MEN1 gene to a small region within chromosome 11q13 by deletion mapping in tumors.Semantic proximity Read ↗

MEN1 intragenic deletions may represent the most prevalent somatic event in sporadic primary hyperparathyroidism.Semantic proximity Read ↗

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