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Article

Loss of heterozygosity in sporadic parathyroid tumours: involvement of chromosome 1 and the MEN1 gene locus in 11q13.

Clinical endocrinology - 1 Jul 2000

Dwight T, Twigg S, Delbridge L, Wong F K, Farnebo F, Richardson A L, Nelson A, Zedenius J, Philips J, Larsson C, Teh B T, Robinson B

Abstract excerpt

OBJECTIVE: Hyperparathyroidism (HPT) is a common endocrine disorder. Several loci of genetic interest have been identified in parathyroid tumours, including the MEN1 gene locus at 11q13; the HPT-JT region at 1q21-q32; and a putative tumour suppressor gene on 1p. We analysed these intervals, which harbour known genes or putative loci associated with familial hyperparathyroidism, in order to clarify the involvement...

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Source

Identifiers

PMID: 10931084
DOI: 10.1046/j.1365-2265.2000.01010.x

Genes

MEN1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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