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Article

Parathyroid MEN1 gene mutations in relation to clinical characteristics of nonfamilial primary hyperparathyroidism.

The Journal of clinical endocrinology and metabolism - 1 Aug 1998

Carling T, Correa P, Hessman O, Hedberg J, Skogseid B, Lindberg D, Rastad J, Westin G, Akerström G

Abstract excerpt

Biochemical signs and severity of symptoms of primary hyperparathyroidism (pHPT) differ among patients, and little is known of any coupling of clinical characteristics of nonfamilial pHPT to genetic abnormalities in the parathyroid tumors. Mutations in the recently identified MEN1 gene at chromosome 11q13 have been found in parathyroid tumors of nonfamilial pHPT. Using microsatellite analysis for loss of...

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Source

Identifiers

PMID: 9709976
DOI: 10.1210/jcem.83.8.4977

Genes

MEN1
PTH

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Parathyroid MEN1 gene mutations in relation to clinical characteristics of nonfamilial primary hyperparathyroidism.PMID 9709976Read ↗

MEN1 gene alterations do not correlate with the phenotype of sporadic primary hyperparathyroidism.Semantic proximity Read ↗

Localization of the MEN1 gene to a small region within chromosome 11q13 by deletion mapping in tumors.Semantic proximity Read ↗

Alterations of the MEN1 gene in sporadic parathyroid tumors.Semantic proximity Read ↗

Analysis of genotype-phenotype correlations and survival outcomes in patients with primary hyperparathyroidism caused by multiple endocrine neoplasia type 1: the experience at a single institution.Semantic proximity Read ↗

The MEN1 gene and associated diseases: an update.Semantic proximity Read ↗

Somatic mutation of the MEN1 gene in parathyroid tumours.Semantic proximity Read ↗

Parathyroid MEN1 Gene Mutations in Relation to Clinical Characteristics of Nonfamilial Primary HyperparathyroidismSemantic proximity Read ↗

Novel somatic MEN1 gene alterations in sporadic primary hyperparathyroidism and correlation with clinical characteristics.Semantic proximity Read ↗

Involvement of the MEN1 gene locus in familial isolated hyperparathyroidism.Semantic proximity Read ↗

Allelic deletions on chromosome 11q13 in multiple tumors from individual MEN1 patients.Semantic proximity Read ↗

Loss of heterozygosity in sporadic parathyroid tumours: involvement of chromosome 1 and the MEN1 gene locus in 11q13.Semantic proximity Read ↗

Clinical and Genetic Analysis of Multiple Endocrine Neoplasia Type 1-Related Primary Hyperparathyroidism in Chinese.Semantic proximity Read ↗

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