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Article

Induction of early B cell factor (EBF) and multiple B lineage genes by the basic helix-loop-helix transcription factor E12.

The Journal of experimental medicine - 17 Aug 1998

Kee B L, Murre C

Abstract excerpt

The transcription factors encoded by the E2A and early B cell factor (EBF) genes are required for the proper development of B lymphocytes. However, the absence of B lineage cells in E2A- and EBF-deficient mice has made it difficult to determine the function or relationship between these proteins. We report the identification of a novel model system in which the role of E2A and EBF in the regulation of multiple B...

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Identifiers

PMID: 9705952
DOI: 10.1084/jem.188.4.699
PMCID: PMC2213347

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Source receipt: pubmed, retrieved 7 Sept 2026.

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