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Article

Regulation of E2A gene expression in B-lymphocyte development.

Molecular immunology - 1 Mar 2004

Zhuang Yuan, Jackson Annette, Pan Lihua, Shen Kang, Dai Meifang

Abstract excerpt

Biochemical and genetic studies have demonstrated that transcription factors encoded by the E2A gene are essential in regulating B lineage specific gene expression and B lineage commitment. However, the mechanism by which E2A regulates B lineage commitment is not known. It has been reported that E2A controls B lineage commitment in a dosage dependent manner. To further investigate this gene dosage effect, we...

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Share to Bone Marrow Cells
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Gene Rearrangement, B-Lymphocyte, Heavy Chain

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Share to Genes, Immunoglobulin

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Source

Identifiers

PMID: 15104122
DOI: 10.1016/j.molimm.2003.11.031

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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