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Article

The establishment of B versus T cell identity.

Trends in immunology - 1 May 2014

Miyazaki Kazuko, Miyazaki Masaki, Murre Cornelis

Abstract excerpt

In B cell progenitors, E-proteins E2A and HEB (HeLa E-box binding protein) are crucial for the induction of a B lineage-specific program of gene expression and for orchestrating the assembly of the immunoglobulin loci. In the thymus E2A and HEB act differently, activating the expression of genes closely associated with the establishment of T cell identity and promoting the rearrangement of T cell receptor (TCR)...

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Identifiers

PMID: 24679436
DOI: 10.1016/j.it.2014.02.009
PMCID: PMC4030559

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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