Article
The absence of the transcription activator TFE3 impairs activation of B cells in vivo.
Molecular and cellular biology - 1 Jun 1997
Merrell K, Wells S, Henderson A, Gorman J, Alt F, Stall A, Calame K
Abstract excerpt
TFE3 is a ubiquitously expressed member of the TFE3/mi family of basic helix loop helix zipper transcription factors. TFE3 binds to muE3 sites located in the immunoglobulin heavy-chain (IgH) intronic enhancer, heavy-chain variable region promoters, the Ig kappa intronic enhancer, and regulatory s...
Topics
- Alleles
- Animals
- B-Lymphocytes
- Basic Helix-Loop-Helix Leucine Zipper Transcription Factors
- Bone Marrow Cells
- Chimera
- Chromosome Mapping
- DNA-Binding Proteins
- Helix-Loop-Helix Motifs
- Leucine Zippers
- Lymphocyte Activation
- Mice
- Mice, Inbred BALB C
- Proteins
- Receptors, IgE
- Spleen
- T-Lymphocytes
- Thymus Gland