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Article

The absence of the transcription activator TFE3 impairs activation of B cells in vivo.

Molecular and cellular biology - 1 Jun 1997

Merrell K, Wells S, Henderson A, Gorman J, Alt F, Stall A, Calame K

Abstract excerpt

TFE3 is a ubiquitously expressed member of the TFE3/mi family of basic helix loop helix zipper transcription factors. TFE3 binds to muE3 sites located in the immunoglobulin heavy-chain (IgH) intronic enhancer, heavy-chain variable region promoters, the Ig kappa intronic enhancer, and regulatory sites in other genes. To understand the role of TFE3 in Ig expression and lymphoid development, we used embryonic stem...

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Identifiers

PMID: 9154832
DOI: 10.1128/MCB.17.6.3335
PMCID: PMC232186

Genes

RAG2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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